A multiple dose study of prasugrel (CS-747), a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy humans

AIMS: This double-blind, placebo-controlled trial was designed to evaluate the pharmacodynamics, pharmacokinetics, safety, and tolerability of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y(12) ADP receptor antagonist compared with clopidogrel, during multiple oral dosing in healthy subjec...

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Hlavní autoři: Jakubowski, Joseph A, Matsushima, Nobuko, Asai, Fumitoshi, Naganuma, Hideo, Brandt, John T, Hirota, Takashi, Freestone, Stephen, Winters, Kenneth J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2007
Témata:
Pharmacodynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203227/
https://ncbi.nlm.nih.gov/pubmed/17076696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02792.x
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