Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response

Matrix metalloproteinases (MMPs) are expressed by T cells and macrophages, but there is a paucity of evidence for their role in immune responses. We have studied mice with deficiencies of stromelysin-1 (MMP-3) or gelatinase B (MMP-9) in a dinitrofluorobenzene (DNFB)-induced model of contact hypersen...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Wang, Min, Qin, Xuejin, Mudgett, John S., Ferguson, Thomas A., Senior, Robert M., Welgus, Howard G.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22011/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.6885
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