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Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response

Matrix metalloproteinases (MMPs) are expressed by T cells and macrophages, but there is a paucity of evidence for their role in immune responses. We have studied mice with deficiencies of stromelysin-1 (MMP-3) or gelatinase B (MMP-9) in a dinitrofluorobenzene (DNFB)-induced model of contact hypersen...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wang, Min, Qin, Xuejin, Mudgett, John S., Ferguson, Thomas A., Senior, Robert M., Welgus, Howard G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.6885
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