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Secreted thrombospondin-1 controls platelet sensitivity to NO
Many functions have been suggested for the large amounts of thrombospondin-1 that are stored in α-granules of platelets. Isenberg et al describe a new role whereby thrombospondin-1 counteracts NO and allows platelet activation to take place in situations in which NO is being generated.
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200842/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-118075 |
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