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Cross-Clade Protective Immune Responses to Influenza Viruses with H5N1 HA and NA Elicited by an Influenza Virus-Like Particle

BACKGROUND: Vaccination is a cost-effective counter-measure to the threat of seasonal or pandemic outbreaks of influenza. To address the need for improved influenza vaccines and alternatives to egg-based manufacturing, we have engineered an influenza virus-like particle (VLP) as a new generation of...

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Detalhes bibliográficos
Main Authors: Bright, Rick A., Carter, Donald M., Crevar, Corey J., Toapanta, Franklin R., Steckbeck, Jonathan D., Cole, Kelly S., Kumar, Niranjan M., Pushko, Peter, Smith, Gale, Tumpey, Terrence M., Ross, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200794/
https://ncbi.nlm.nih.gov/pubmed/18231588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001501
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