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Autoantibodies to double-stranded (ds)DNA immunoprecipitate 18S ribosomal RNA by virtue of their interaction with ribosomal protein S1 and suppress in vitro protein synthesis

We report that four systemic lupus erythematosus (SLE) patient sera containing anti-dsDNA antibodies, three affinity-purified anti-dsDNA IgG, and a human anti-dsDNA MoAb (33.H11) immunoprecipitate 18S ribosomal RNA from DNase-treated (32)P-labelled MOLT4 cell extract. This 18S RNA precipitation was...

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Autors principals: TSUZAKA, K, WINKLER, T H, KALDEN, J R, REICHLIN, M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200613/
https://ncbi.nlm.nih.gov/pubmed/8973619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-869.x
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