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Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) production during murine endotoxaemia

IL-10 is an endogenous antiinflammatory cytokine that inhibits TNF biosynthesis and protects mice from lipopolysaccharide (LPS)-induced lethality. As synthetic glucocorticoids are widely used as antiinflammatory agents, we analysed the effects of methylprednisolone administration on IL-10 biosynthes...

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Detalhes bibliográficos
Main Authors: MARCHANT, A, AMRAOUI, Z, GUEYDAN, C, BRUYNS, C, LE MOINE, O, VANDENABEELE, P, FIERS, W, BUURMAN, W A, GOLDMAN, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200560/
https://ncbi.nlm.nih.gov/pubmed/8870704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-799.x
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