IL-12 stimulation but not B7 expression increases melanoma killing by patient cytotoxic T lymphocytes (CTL)

Recent studies have demonstrated that rodent tumour cells engineered to secrete a variety of cytokines, or to express foreign antigens, MHC molecules or co-stimulatory molecules, are rejected by syngeneic animals. These observations have led to the initiation of a number of clinical trials using gen...

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Detalhes bibliográficos
Main Authors: DE WIT, D, FLEMMING, C L, HARRIS, J D, PALMER, K J, MOORE, J S, GORE, M E, COLLINS, M K L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1996
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200495/
https://ncbi.nlm.nih.gov/pubmed/8706345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-773.x
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