Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies

We have previously described two human cold agglutinin MoAbs 216 and A6(H4C5), that are derived from the VH4-34 (VH4.21) gene that bind specifically to a cell surface ligand on human B lymphocytes. In this study, we report that binding of 216 and A6(H4C5) leads to rapid killing of target B cells. Th...

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Detalhes bibliográficos
Main Authors: BHAT, N M, BIEBER, M M, STEVENSON, F K, TENG, N N H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1996
Assuntos:
Rapid Publications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200465/
https://ncbi.nlm.nih.gov/pubmed/8697629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-733.x
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