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IL-12 protects mice against pulmonary and disseminated infection caused by Cryptococcus neoformans

We examined the role of IL-12 in host resistance to Cryptococcus neoformans using a murine model of pulmonary and disseminated infection. In this model, mice were infected intratracheally with viable yeast cells. Mice untreated with IL-12 allowed an uncontrolled multiplication of yeast cells in the...

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Autori principali: KAWAKAMI, K, TOHYAMA, M, XIE, Q, SAITO, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200435/
https://ncbi.nlm.nih.gov/pubmed/8625510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.14723.x
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