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FcγRIIa polymorphism in systemic lupus erythematosus (SLE): no association with disease

An allotypic variant of FcγRIIa, FcγRIIa-HR (FcγRIIa-R131), has been shown in vitroto reduce the capacity of phagocytic cells to bind and internalize IgG-containing immune complexes. Our aim was to determine whether this allotypic variant was associated with susceptibility to SLE and the development...

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Autores principales: BOTTO, M, THEODORIDIS, E, THOMPSON, E M, BEYNON, H L C, BRIGGS, D, ISENBERG, D A, WALPORT, M J, DAVIES, K A
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200413/
https://ncbi.nlm.nih.gov/pubmed/8625518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.33740.x
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