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An experimental solution for the Luria–Delbrück fluctuation problem in measuring hypermutation rates

A cell line harboring all trans-acting elements necessary for hypermutation was transfected with a plasmid harboring the major cis-acting elements plus a green fluorescent protein gene containing a premature chain-termination codon. Transfected cells do not fluoresce unless the stop codon reverts. W...

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Sonraí Bibleagrafaíochta
Main Authors: Bachl, Jürgen, Dessing, Mark, Olsson, Carina, von Borstel, R. C., Steinberg, Charles
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC22004/
https://ncbi.nlm.nih.gov/pubmed/10359801
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