An experimental solution for the Luria–Delbrück fluctuation problem in measuring hypermutation rates
A cell line harboring all trans-acting elements necessary for hypermutation was transfected with a plasmid harboring the major cis-acting elements plus a green fluorescent protein gene containing a premature chain-termination codon. Transfected cells do not fluoresce unless the stop codon reverts. W...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1999
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.6847 |
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