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Effect of the expression of DRαEβ(NOD) molecule on the development of insulitis and diabetes in the non-obese diabetic (NOD) mouse

Previous studies have shown that a transgenic I-Eα gene, the mouse homologue of human DRα gene, prevents the development of insulitis and hence of diabetes in NOD mice. To investigate the mechanism of this prevention, we generated two strains of NOD mice expressing DRαEβ molecule: DRα-24-NOD express...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: YAMANE, K, YAMAMOTO, K, YOSHIKAWA, Y, SASAZUKI, T
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200308/
https://ncbi.nlm.nih.gov/pubmed/8565273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.00892.x
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