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Effect of the expression of DRαEβ(NOD) molecule on the development of insulitis and diabetes in the non-obese diabetic (NOD) mouse
Previous studies have shown that a transgenic I-Eα gene, the mouse homologue of human DRα gene, prevents the development of insulitis and hence of diabetes in NOD mice. To investigate the mechanism of this prevention, we generated two strains of NOD mice expressing DRαEβ molecule: DRα-24-NOD express...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200308/ https://ncbi.nlm.nih.gov/pubmed/8565273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.00892.x |
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