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Age-Related Atrophy of Motor Axons in Mice Deficient in the Mid-Sized Neurofilament Subunit

Neurofilaments are central determinants of the diameter of myelinated axons. It is less clear whether neurofilaments serve other functional roles such as maintaining the structural integrity of axons over time. Here we show that an age-dependent axonal atrophy develops in the lumbar ventral roots of...

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Auteurs principaux: Elder, Gregory A., Friedrich, Victor L., Margita, Alla, Lazzarini, Robert A.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199745/
https://ncbi.nlm.nih.gov/pubmed/10402469
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