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Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content

Neurofilaments (NFs) are prominent components of large myelinated axons and probably the most abundant of neuronal intermediate filament proteins. Here we show that mice with a null mutation in the mid-sized NF (NF-M) subunit have dramatically decreased levels of light NF (NF-L) and increased levels...

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Autors principals: Elder, Gregory A., Friedrich, Victor L., Bosco, Paolo, Kang, Chulho, Gourov, Andrei, Tu, Pang-Hsien, Lee, Virginia M.-Y., Lazzarini, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132741/
https://ncbi.nlm.nih.gov/pubmed/9566972
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