Myosin Light Chain Kinase Functions Downstream of Ras/ERK to Promote Migration of Urokinase-Type Plasminogen Activator-Stimulated Cells in an Integrin-Selective Manner

Urokinase-type plasminogen activator (uPA) activates the mitogen activated protein (MAP) kinases, extracellular signal-regulated kinase (ERK) 1 and 2, in diverse cell types. In this study, we demonstrate that uPA stimulates migration of MCF-7 breast cancer cells, HT 1080 fibrosarcoma cells, and uPAR...

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Autori principali: Nguyen, Diem H.D., Catling, Andrew D., Webb, Donna J., Sankovic, Mauricio, Walker, Lori A., Somlyo, Avril V., Weber, Michael J., Gonias, Steven L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199739/
https://ncbi.nlm.nih.gov/pubmed/10402467
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