Intracellular Localization of Proteasomal Degradation of a Viral Antigen

To better understand proteasomal degradation of nuclear proteins and viral antigens we studied mutated forms of influenza virus nucleoprotein (NP) that misfold and are rapidly degraded by proteasomes. In the presence of proteasome inhibitors, mutated NP (dNP) accumulates in highly insoluble ubiquiti...

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Detalhes bibliográficos
Main Authors: Antón, Luis C., Schubert, Ulrich, Bacík, Igor, Princiotta, Michael F., Wearsch, Pamela A., Gibbs, James, Day, Patricia M., Realini, Claudio, Rechsteiner, Martin C., Bennink, Jack R., Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199725/
https://ncbi.nlm.nih.gov/pubmed/10402464
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