A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation

Previous work has shown that Xenopus blastula cells sense activin concentration by assessing the absolute number of occupied receptors per cell (100 and 300 molecules of bound activin activate Xbra and Xgsc transcription, respectively; a difference of only 3-fold). We now ask how quantitative differ...

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Detaylı Bibliyografya
Asıl Yazarlar: Shimizu, Kazuya, Gurdon, J. B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC21994/
https://ncbi.nlm.nih.gov/pubmed/10359791
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