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AS601245, a c-Jun NH(2)-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils
BACKGROUND AND PURPOSE. Based on their proven ability, in animal models of stroke, to reduce damage to brain grey matter, many drugs have been tested in clinical trials but without success. Failure to save axons from injury and to protect functional outcome has been proposed as the major reason for...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199388/ https://ncbi.nlm.nih.gov/pubmed/18026128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707574 |
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