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Dinuclear Zinc-Catalyzed Asymmetric Desymmetrization of Acyclic 2-Substituted-1,3-Propanediols: A Powerful Entry into Chiral Building Blocks

The asymmetric acylation of meso 2-substituted-1,3-propanediols using an amphoteric chiral dinuclear zinc catalyst is described. It is has been demonstrated that both 2-alkyl- and 2-aryl-1,3-propanediols can be desymmetrized in high yields and enantioselectivities using the same family of ligands. G...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Trost, Barry M., Malhotra, Sushant, Mino, Takashi, Rajapaksa, Naomi S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199377/
https://ncbi.nlm.nih.gov/pubmed/18655088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200800623
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