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α(v)β(3) integrin expression up-regulates cdc2, which modulates cell migration

The α(v)β(3) integrin has been shown to promote cell migration through activation of intracellular signaling pathways. We describe here a novel pathway that modulates cell migration and that is activated by α(v)β(3) and, as downstream effector, by cdc2 (cdk1). We report that α(v)β(3) expression in L...

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Autors principals: Manes, Thomas, Zheng, Duo-Qi, Tognin, Simona, Woodard, Amy S., Marchisio, Pier Carlo, Languino, Lucia R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199360/
https://ncbi.nlm.nih.gov/pubmed/12771130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200212172
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