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Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

We discovered that many proteins located in the kinetochore outer domain, but not the inner core, are depleted from kinetochores and accumulate at spindle poles when ATP production is suppressed in PtK1 cells, and that microtubule depolymerization inhibits this process. These proteins include the mi...

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Bibliografiske detaljer
Main Authors: Howell, B.J., McEwen, B.F., Canman, J.C., Hoffman, D.B., Farrar, E.M., Rieder, C.L., Salmon, E.D.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199338/
https://ncbi.nlm.nih.gov/pubmed/11756470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105093
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