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Sickle cell disease and nitric oxide: A paradigm shift?

Traditionally the pathophysiology of sickle cell disease is thought to result from the polymerization of hemoglobin S in red cells, under hypoxic conditions, resulting in the occlusion of blood vessels. Adhesion of cells to the venular endothelium also appears to play a role. Recent studies have als...

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Detalhes bibliográficos
Main Authors: Mack, A. Kyle, Kato, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199240/
https://ncbi.nlm.nih.gov/pubmed/16517208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2006.01.010
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