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Enhanced Expression of the α7β1 Integrin Reduces Muscular Dystrophy and Restores Viability in Dystrophic Mice

Muscle fibers attach to laminin in the basal lamina using two distinct mechanisms: the dystrophin glycoprotein complex and the α7β1 integrin. Defects in these linkage systems result in Duchenne muscular dystrophy (DMD), α2 laminin congenital muscular dystrophy, sarcoglycan-related muscular dystrophy...

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Autors principals: Burkin, Dean J., Wallace, Gregory Q., Nicol, Kimberly J., Kaufman, David J., Kaufman, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199213/
https://ncbi.nlm.nih.gov/pubmed/11257121
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