Membrane Fas Ligand Kills Human Peripheral Blood T Lymphocytes, and Soluble Fas Ligand Blocks the Killing

It has been believed that the Fas expressed on human peripheral blood T cells (PBT) is nonfunctional, because these cells are insensitive to agonistic anti-Fas/Apo-1 mAbs that efficiently kill in vitro–activated T cells and many Fas-expressing cell lines. Here, we demonstrate that membrane-bound Fas...

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Bibliographic Details
Main Authors: Suda, Takashi, Hashimoto, Hideo, Tanaka, Masato, Ochi, Takahiro, Nagata, Shigekazu
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199173/
https://ncbi.nlm.nih.gov/pubmed/9396774
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