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The Thrombopoietin Receptor Can Mediate Proliferation without Activation of the Jak-STAT Pathway

Cytokine receptors of the hematopoietic receptor superfamily lack intrinsic tyrosine kinase domains for the intracellular transmission of their signals. Instead all members of this family associate with Jak family nonreceptor tyrosine kinases. Upon ligand stimulation of the receptors, Jaks are activ...

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Autori principali: Dorsch, Marion, Fan, Pang-Dian, Danial, Nika N., Rothman, Paul B., Goff, Stephen P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199166/
https://ncbi.nlm.nih.gov/pubmed/9396763
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