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The Thrombopoietin Receptor Can Mediate Proliferation without Activation of the Jak-STAT Pathway

Cytokine receptors of the hematopoietic receptor superfamily lack intrinsic tyrosine kinase domains for the intracellular transmission of their signals. Instead all members of this family associate with Jak family nonreceptor tyrosine kinases. Upon ligand stimulation of the receptors, Jaks are activ...

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Détails bibliographiques
Auteurs principaux: Dorsch, Marion, Fan, Pang-Dian, Danial, Nika N., Rothman, Paul B., Goff, Stephen P.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199166/
https://ncbi.nlm.nih.gov/pubmed/9396763
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