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Suppressive Role of B Cells in Chronic Colitis of T Cell Receptor α Mutant Mice
The role of antibodies (Abs) in the development of chronic colitis in T cell receptor (TCR)-α(−/−) mice was explored by creating double mutant mice (TCR-α(−/−) × immunoglobulin (Ig)μ(−/−)), which lack B cells. TCR-α(−/−) × Igμ(−/−) mice spontaneously developed colitis at an earlier age, and the coli...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199135/ https://ncbi.nlm.nih.gov/pubmed/9362534 |
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