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Suppressive Role of B Cells in Chronic Colitis of  T Cell Receptor α Mutant Mice

The role of antibodies (Abs) in the development of chronic colitis in T cell receptor (TCR)-α(−/−) mice was explored by creating double mutant mice (TCR-α(−/−) × immunoglobulin (Ig)μ(−/−)), which lack B cells. TCR-α(−/−) × Igμ(−/−) mice spontaneously developed colitis at an earlier age, and the coli...

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Bibliografiske detaljer
Main Authors: Mizoguchi, Atsushi, Mizoguchi, Emiko, Smith, R. Neal, Preffer, Frederic I., Bhan, Atul K.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199135/
https://ncbi.nlm.nih.gov/pubmed/9362534
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