The Macrophage Scavenger Receptor Type A Is Expressed by Activated Macrophages and Protects the Host Against Lethal Endotoxic Shock

During gram-negative bacterial infections, lipopolysaccharide (LPS) stimulates primed macrophages (Mφ) to release inflammatory mediators such as tumor necrosis factor (TNF)-α, which can cause hypotension, organ failure, and often death. Several different receptors on Mφ have been shown to bind LPS,...

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Main Authors: Haworth, Richard, Platt, Nick, Keshav, Satish, Hughes, Derralynn, Darley, Elisabeth, Suzuki, Hiroshi, Kurihara, Yukiko, Kodama, Tatsuhiko, Gordon, Siamon
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199123/
https://ncbi.nlm.nih.gov/pubmed/9348300
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