How Many Thymocytes Audition for Selection?

T cell maturation requires the rearrangement of clonotypic T cell receptors (TCR) capable of interacting with major histocompatibility complex (MHC) ligands to initiate positive and negative selection. Only 3–5% of thymocytes mature to join the peripheral T cell pool. To investigate the basis for th...

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Detaylı Bibliyografya
Asıl Yazarlar: Merkenschlager, Matthias, Graf, Daniel, Lovatt, Matthew, Bommhardt, Ursula, Zamoyska, Rose, Fisher, Amanda G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 1997
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199071/
https://ncbi.nlm.nih.gov/pubmed/9314563
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