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CD3 Ligation on Immature Thymocytes Generates Antagonist-like Signals Appropriate for CD8 Lineage Commitment, Independently of  T Cell Receptor Specificity

The signals that direct differentiation of T cells to the CD4 or CD8 lineages in the thymus remain poorly understood. Although it has been relatively easy to direct differentiation of CD4 single positive (CD4(+)) cells using combinations of antibodies and pharmacological agents that mimic receptor e...

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Detalhes bibliográficos
Main Authors: Albert Basson, M., Bommhardt, Ursula, Cole, Michael S., Tso, J. Yun, Zamoyska, Rose
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212221/
https://ncbi.nlm.nih.gov/pubmed/9547336
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