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Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism

Antigen-presenting cells (APC) degrade endocytosed antigens into peptides that are bound and presented to T cells by major histocompatibility complex (MHC) class II molecules. Class II molecules are delivered to endocytic compartments by the class II accessory molecule invariant chain (Ii), which it...

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Detalhes bibliográficos
Main Authors: Villadangos, José A., Riese, Richard J., Peters, Christoph, Chapman, Harold A., Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199027/
https://ncbi.nlm.nih.gov/pubmed/9254653
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