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Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules

Heat shock factor 1 (HSF1) is essential for the stress-induced expression of heat shock genes. On exposure to heat shock, HSF1 localizes within seconds to discrete nuclear granules. On recovery from heat shock, HSF1 rapidly dissipates from these stress granules to a diffuse nucleoplasmic distributio...

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Autori principali: Jolly, Caroline, Usson, Yves, Morimoto, Richard I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21990/
https://ncbi.nlm.nih.gov/pubmed/10359787
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