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Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

The existence of multiple heat shock factor (HSF) genes in higher eukaryotes has promoted questions regarding the functions of these HSF family members, especially with respect to the stress response. To address these questions, we have used polyclonal antisera raised against mouse HSF1 and HSF2 to...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Sarge, K D, Murphy, S P, Morimoto, R I
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441385/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1392
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