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The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

According to current understanding, cytoplasmic events including activation of protease cascades and mitochondrial permeability transition (PT) participate in the control of nuclear apoptosis. However, the relationship between protease activation and PT has remained elusive. When apoptosis is induce...

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Библиографические подробности
Главные авторы: Susin, Santos A., Zamzami, Naoufal, Castedo, Maria, Daugas, Eric, Wang, Hong-Gang, Geley, Stephan, Fassy, Florence, Reed, John C., Kroemer, Guido
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 1997
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198951/
https://ncbi.nlm.nih.gov/pubmed/9206994
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