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The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

According to current understanding, cytoplasmic events including activation of protease cascades and mitochondrial permeability transition (PT) participate in the control of nuclear apoptosis. However, the relationship between protease activation and PT has remained elusive. When apoptosis is induce...

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Detalhes bibliográficos
Main Authors: Susin, Santos A., Zamzami, Naoufal, Castedo, Maria, Daugas, Eric, Wang, Hong-Gang, Geley, Stephan, Fassy, Florence, Reed, John C., Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198951/
https://ncbi.nlm.nih.gov/pubmed/9206994
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