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The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

We have investigated how Wnt and vitamin D receptor signals regulate epidermal differentiation. Many epidermal genes induced by β-catenin, including the stem cell marker keratin 15, contain vitamin D response elements (VDREs) and several are induced independently of TCF/Lef. The VDR is required for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pálmer, Héctor G., Anjos-Afonso, Fernando, Carmeliet, Geert, Takeda, Hikaru, Watt, Fiona M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198947/
https://ncbi.nlm.nih.gov/pubmed/18213391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001483
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