Phosphatidylinositol 4,5-Bisphosphate Induces Actin Stress-Fiber Formation and Inhibits Membrane Ruffling in Cv1 Cells

Phosphatidylinositol 4,5 bisphosphate (PIP(2)) is widely implicated in cytoskeleton regulation, but the mechanisms by which PIP(2) effect cytoskeletal changes are not defined. We used recombinant adenovirus to infect CV1 cells with the mouse type I phosphatidylinositol phosphate 5-kinase α (PIP5KI),...

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Autors principals: Yamamoto, Masaya, Hilgemann, Donald H., Feng, Siyi, Bito, Haruhiko, Ishihara, Hisamitsu, Shibasaki, Yoshikazu, Yin, Helen L.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198810/
https://ncbi.nlm.nih.gov/pubmed/11238445
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