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Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p

Cell cycle progression is driven by waves of cyclin expression coupled with regulated protein degradation. An essential step for initiating mitosis is the inactivation of proteolysis mediated by the anaphase-promoting complex/cyclosome (APC/C) bound to its regulator Cdh1p/Hct1p. Yeast APC(Cdh1) was...

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Detalles Bibliográficos
Main Authors: Huang, James N., Park, Iha, Ellingson, Eric, Littlepage, Laurie E., Pellman, David
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196868/
https://ncbi.nlm.nih.gov/pubmed/11448992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200102007
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