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Cross-linking of Fas By Antibodies to a Peculiar Domain of gp120 V3 Loop Can Enhance T Cell Apoptosis in HIV-1–infected Patients

Previous studies have demonstrated that T cell–reactive antibodies in HIV-1 infection contribute to lymphocyte depletion by cytotoxicity that involves differential membrane targets, such as the 43.5-kD receptor on CEM cells. Here, we show that these antibodies bind Fas as result of a molecular mimic...

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Bibliografiske detaljer
Main Authors: Silvestris, Franco, Nagata, Shigekazu, Cafforio, Paola, Silvestris, Nicola, Dammacco, Franco
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196362/
https://ncbi.nlm.nih.gov/pubmed/8976184
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