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On the Key Role of Secondary Lymphoid Organs in Antiviral Immune Responses Studied in Alymphoplastic (aly/aly) and Spleenless (Hox11(−) (/−)) Mutant Mice

The role of the spleen and of other organized secondary lymphoid organs for the induction of protective antiviral immune responses was evaluated in orphan homeobox gene 11 knockout mice (Hox11(−/−)) lacking the spleen, and in homozygous alymphoplastic mutant mice (aly/aly) possessing a structurally...

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Autors principals: Karrer, Urs, Althage, Alana, Odermatt, Bernhard, Roberts, Charles W.M., Korsmeyer, Stanley J., Miyawaki, Shigeki, Hengartner, Hans, Zinkernagel, Rolf M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196355/
https://ncbi.nlm.nih.gov/pubmed/9182687
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