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Lymphotoxin-α (LTα) Supports Development of Splenic Follicular Structure That Is Required for IgG Responses
LTα-deficient (LTα(−/−)) mice show altered splenic microarchitecture. This includes loss of normal B cell–T cell compartmentalization, of follicular dendritic cell (FDC) clusters, and of ability to form germinal centers (GC). LTα(−/−) mice immunized with sheep red blood cells (SRBC) produced high le...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196348/ https://ncbi.nlm.nih.gov/pubmed/9182683 |
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