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CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro

Chemokine receptors serve as coreceptors for HIV entry into CD4(+) cells. Their expression is thought to determine the tropism of viral strains for different cell types, and also to influence susceptibility to infection and rates of disease progression. Of the chemokine receptors, CCR5 is the most i...

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Detalhes bibliográficos
Main Authors: Wu, Lijun, Paxton, William A., Kassam, Nasim, Ruffing, Nancy, Rottman, James B., Sullivan, Nancy, Choe, Hyeryun, Sodroski, Joseph, Newman, Walter, Koup, Richard A., Mackay, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196298/
https://ncbi.nlm.nih.gov/pubmed/9151905
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