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Light Chain Usage in Anti–double-stranded DNA B Cell Subsets: Role in Cell Fate Determination

Two major mechanisms for the regulation of autoreactive B cells that arise in the bone marrow are functional silencing (anergy) and deletion. Studies to date suggest that low avidity interactions between B cells and autoantigen lead to B cell silencing, whereas high avidity interactions lead to dele...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Spatz, Linda, Saenko, Vladimir, Iliev, Andrey, Jones, Lori, Geskin, Larisa, Diamond, Betty
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196257/
https://ncbi.nlm.nih.gov/pubmed/9104818
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