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Structural Analysis of the Catalytic Core of Human Telomerase RNA by FRET and Molecular Modeling,

Telomerase is the ribonucleoprotein reverse transcriptase involved in the maintenance of the telomeres, the termini of eukaryotic chromosomes. The RNA component of human telomerase (hTR) consists of 451 nucleotides with the 5′ half folding into a highly conserved catalytic core comprising the templa...

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Detalhes bibliográficos
Main Authors: Gavory, Gérald, Symmons, Martyn F., Ghosh, Yamuna Krishnan, Klenerman, David, Balasubramanian, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196208/
https://ncbi.nlm.nih.gov/pubmed/17073451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061150a
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