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Investigating a Quadruplex–Ligand Interaction by Unfolding Kinetics

We have investigated the interaction of the intramolecular human telomeric DNA G-quadruplex with a hemicyanine–peptide ligand, by studying the rate of quadruplex opening with a complementary DNA oligonucleotide. By employing a minimal kinetic model, the relationship between the observed rate of quad...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Green, Jeremy J., Ladame, Sylvain, Ying, Liming, Klenerman, David, Balasubramanian, Shankar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196206/
https://ncbi.nlm.nih.gov/pubmed/16866537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0615425
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