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Investigating a Quadruplex–Ligand Interaction by Unfolding Kinetics
We have investigated the interaction of the intramolecular human telomeric DNA G-quadruplex with a hemicyanine–peptide ligand, by studying the rate of quadruplex opening with a complementary DNA oligonucleotide. By employing a minimal kinetic model, the relationship between the observed rate of quad...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196206/ https://ncbi.nlm.nih.gov/pubmed/16866537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0615425 |
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