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Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo
Evidence is provided that proteolytic cleavage of collagen type IV results in the exposure of a functionally important cryptic site hidden within its triple helical structure. Exposure of this cryptic site was associated with angiogenic, but not quiescent, blood vessels and was required for angiogen...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196184/ https://ncbi.nlm.nih.gov/pubmed/11535623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200103111 |
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