Matrix Metalloproteinase-9-Dependent Exposure of a Cryptic Migratory Control Site in Collagen is Required before Retinal Angiogenesis

Retinal neovascularization is a leading cause of human blindness. However, little is known concerning the molecular mechanisms controlling retinal neovascularization in vivo. Here we provide evidence that exposure of a collagen type IV cryptic epitope detected by monoclonal antibody (mAb) HUIV26, de...

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Main Authors: Hangai, Masanori, Kitaya, Norihiko, Xu, Jingsong, Chan, Candy K., Kim, Jenny J., Werb, Zena, Ryan, Stephen J., Brooks, Peter C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2002
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867273/
https://ncbi.nlm.nih.gov/pubmed/12368215
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